| Bioactivity | UB-165 is a nAChR agonist, being a full agonist of the α3β2 isoform and a partial agonist of the α4β2* isoform, with a Ki value of 0.27 nM for [3H]-nicotine binding in rat brain[1]. |
| Invitro | UB-165 刺激 [3H]-多巴胺从纹状体突触释放，EC50 值为 88 nM[1]。 |
| Name | UB-165 |
| CAS | 200432-86-6 |
| Formula | C13H15ClN2 |
| Molar Mass | 234.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sharples CG, et al. UB-165: a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes. J Neurosci. 2000 Apr 15;20(8):2783-91. |