| Bioactivity | UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM[1]. |
| Target | IC50: 12 nM (Ferroptosis) |
| In Vivo | No toxicity is observed in mice after repeated injections of UAMC-3203 (20 µmol/kg; injected intraperitoneally; daily, over a period of 4 weeks)[1]. Animal Model: |
| Name | UAMC-3203 hydrochloride |
| CAS | 2271358-65-5 |
| Formula | C25H38ClN5O2S |
| Molar Mass | 508.12 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140. |