Bioactivity | Tyrosinase-IN-35 (compound 6g) is a human tyrosinase inhibitor (IC50: 2.09 μM), which is more potent than Kojic Acid (HY-W050154) (IC50: 16.38 μM). Tyrosinase-IN-35 can reduce the melanin content of melanoma B16F10 cells in vitro at doses of 4 μM and 8 μM[1]. |
Target | IC50: 2.09 μM (Tyrosinase) |
CAS | 1613467-47-2 |
Formula | C17H15N5OS |
Molar Mass | 337.40 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kinetic studies, molecular docking, and antioxidant activity of novel 1,3-diphenyl pyrazole-thiosemicarbazone with anti-tyrosinase and anti-melanogenesis properties |