Bioactivity | Tyrosinase-IN-29 (compound 5c) is a potent inhibitor of tyrosinase abTYR (IC50: 6.11 μM). Tyrosinase-IN-29 can be used to further study the inhibition of skin hyperpigmentation[1]. |
Target | IC50: 6.11 μM (abTYR) |
CAS | 408335-66-0 |
Formula | C10H9NO2 |
Molar Mass | 175.18 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jacobs ME, Petzer JP, Pretorius J, Cloete SJ, Crous C, Petzer A. Synthesis and evaluation of 3-hydroxyquinolin-2(1H)-one derivatives as inhibitors of tyrosinase. Bioorg Med Chem Lett. 2024 May 31;109:129823. |