| Bioactivity | Tyroserleutide hydrochloride, isolated from the degradation products of porcine spleen[1], is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo[2]. | ||||||
| Invitro | Tyroserleutide (YSL) exhibits immuno-modulating effects, such as enhancing concanavalin (ConA) induced proliferation of mouse spleen lymphocytes, phagocytosis of mouse peritoneal macrophages, and the activity of natural killer (NK) cells[1].Tyroserleutide (YSL), an immunologically therapeutic tripeptide, can promote hepatocarcinoma cell (H22) apoptosis through downregulating Bcl-2 and cyclin D1 expression[2]. Tyroserleutide is an ideal choice for inducing apoptosis of liver tumor cells[2]. Tyroserleutide inhibits tumor growth and does not cause severe toxicities in the major organs. Tyroserleutide can inhibit tumor cell migration[2]. | ||||||
| Name | Tyroserleutide hydrochloride | ||||||
| CAS | 852982-42-4 | ||||||
| Formula | C18H28ClN3O6 | ||||||
| Molar Mass | 417.88 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
Tyroserleutide hydrochloride
CAS: 852982-42-4 F: C18H28ClN3O6 W: 417.88
Tyroserleutide hydrochloride, isolated from the degradation products of porcine spleen, is a small molecular tripeptide
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