| Bioactivity | Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle[1][2][3]. | ||||||||||||
| Invitro | Tylosin exerts antibacterial effects by binding to 23S rRNA of the bacterial ribosomal 50S subunit [1].Tylosin also prevents growth of Gram-negative strains, with MICs of 64 μg/mL, 32 μg/mL, 512 μg/mL and 1 μg/mL for M. haemolytica 11935, P. multocida 4407, E. coli ATCC 25922 and E. coli AS19rlmAI, respectively[3]. | ||||||||||||
| Name | Tylosin | ||||||||||||
| CAS | 1401-69-0 | ||||||||||||
| Formula | C46H77NO17 | ||||||||||||
| Molar Mass | 916.10 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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