| Bioactivity | Tyk2-IN-18 (compound 86) is a potent tyrosine kinase 2 (Tyk2) inhibitor. Tyk2-IN-18 inhibits JAK2-JH2, with an IC50 of ＜10 nM[1][2]. |
| CAS | 3024860-29-2 |
| Formula | C21H24F2N4O3 |
| Molar Mass | 418.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ram W. Sabnis. Novel Tyrosine Kinase 2 Inhibitors for Treating Autoimmune and Inflammatory Diseases. ACS Med. Chem. Lett. May 16, 2024. [2]. Jeffrey Vessels, et al. Tyrosine kinase 2 inhibitors and uses thereof. WO2023250064A1. 2023-12-28. |
Tyk2-IN-18
CAS: 3024860-29-2 F: C21H24F2N4O3 W: 418.44
Tyk2-IN-18 (compound 86) is a potent tyrosine kinase 2 (Tyk2) inhibitor. Tyk2-IN-18 inhibits JAK2-JH2, with an IC50 of
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