Bioactivity | Tyk2-IN-16 is a selective and potent TYK2 inhibitor with an IC50 of <10 nM for TYK2-JH2. Tyk2-IN-16 inhibits pSTAT4 with an IC50 of <10 nM in NK92 cells (WO2023220046A1; compound 184)[1]. |
CAS | 3010874-30-0 |
Formula | C20H20F2N8O |
Molar Mass | 426.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. TeYu CHEN, et al. Tyk2 inhibitors. WO2023220046A1. |