| Bioactivity | Tubulin/NRP1-IN-1 (compound TN-2) is a dual inhibitor of Tubulin and NRP1 with IC50s of 0.71 and 0.85 μM, respectively. Tubulin/NRP1-IN-1 significantly inhibits the viability of prostate tumor cell lines and induces apoptosis[1]. |
| Name | Tubulin/NRP1-IN-1 |
| CAS | 2983719-82-8 |
| Formula | C28H37N5O8 |
| Molar Mass | 571.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zheng L, et al. Discovery of a Dual Tubulin and Neuropilin-1 (NRP1) Inhibitor with Potent In Vivo Anti-Tumor Activity via Pharmacophore-based Docking Screening, Structure Optimization, and Biological Evaluation. J Med Chem. 2023 Dec 14;66(23):16187-16200. |
Tubulin/NRP1-IN-1
CAS: 2983719-82-8 F: C28H37N5O8 W: 571.62
Tubulin/NRP1-IN-1 (compound TN-2) is a dual inhibitor of Tubulin and NRP1 with IC50s of 0.71 and 0.85 μM, respectively.
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