Tubulin polymerization-IN-60_product_DataBase

Bioactivity	Tubulin polymerization-IN-60 (BF3) is a tubulin polymerization inhibitor with anticancer activity. Tubulin polymerization-IN-60 (BF3) belongs to the colchicine binding site inhibitors (CBSIs) and disturbs cell cycle progression leading to G2/M arrest and apoptosis[1].
Invitro	Tubulin polymerization-IN-60 (BF3) 以剂量依赖性方式抑制细胞增殖，对于A375、MDA-MB435S 和 WM9 细胞，其IC50 分别为 0.09 ± 0.01 μM、0.11 ± 0.01 μM 和 0.18 ± 0.05 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Tubulin polymerization-IN-60 相关抗体:
CAS	2361303-91-3
Formula	C25H22O6
Molar Mass	418.44
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Magdalena Perużyńska, et al. Microtubule destabilising activity of selected 7-methoxy-2-phenylbenzo[b]furan derivative against primary and metastatic melanoma cells. Eur J Pharmacol. 2024 Feb 5:964:176308.

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