| Bioactivity | Tubulin polymerization-IN-50 (compound 7n) is a inhibitor of tubulin polymerization, with the IC50 of 5.05 μM in SK-Mel-28 cells. Tubulin polymerization-IN-50 induces the cell cycle arrest in the G2/M phase[1]. |
| Target | 5.05 μM(SK-Mel-28 cells) |
| Name | Tubulin polymerization-IN-50 |
| Formula | C24H20FN3O3 |
| Molar Mass | 417.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Laxmikeshav K et al. Benzimidazole derivatives as tubulin polymerization inhibitors: Design, synthesis and in vitro cytotoxicity studies [published online ahead of print, 2023 Oct 3]. Bioorg Med Chem Lett. 2023;96:129494. |
Tubulin polymerization-IN-50
CAS: F: C24H20FN3O3 W: 417.43
Tubulin polymerization-IN-50 (compound 7n) is a inhibitor of tubulin polymerization, with the IC50 of 5.05 μM in SK-Mel
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