Tubulin polymerization-IN-46_product_DataBase

Bioactivity	Tubulin polymerization-IN-46 (compound 9q) is a microtubule/Tubulin inhibitor that inhibits tubulin polymerization and induces apoptosis. Tubulin polymerization-IN-46 inhibits mitosis and arrests MCF-7 cells in the G2/M phase. Tubulin polymerization-IN-46 has anti-proliferative activity against MCF-7 breast cancer cells with an IC50 of 10 nM[1].
Invitro	Tubulin polymerization-IN-46 (compound 9q) (0.5 μM；16 小时）可诱导 MCF-7 乳腺癌细胞中微管网络解聚[1]。 0 --> Tubulin polymerization-IN-46 相关抗体:
Name	Tubulin polymerization-IN-46
Formula	C22H25NO6
Molar Mass	399.44
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Wang S, et al. Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells. Pharmaceuticals (Basel). 2023 Jul 13;16(7):1000..

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