| Bioactivity | Tubulinpolymer-in-44 (compound 7w) is a strong and effective Tubulin inhibitor, with an IC50 value of 0.21 μM. Tubulinpolymer-in-44 induces apoptosis by arresting G2/M phase, which can be used for cancer research. |
| Target | IC50: 0.21 μM (Tubulin) |
| Invitro | Tubulin polymerization-IN-44 (0.42 μM, 24 h- 48 h ) 有良好的抑制SGC-7910 细胞增殖活性IC50值为0.21 μM。 Cell Cycle Analysis Cell Line: |
| In Vivo | Tubulin Polymers-in-44（5-20 mg/kg，每隔一天）可抑制乳腺癌 4T1 细胞小鼠模型的肿瘤生长，且不会减少体重减轻。 Animal Model: |
| Name | Tubulin polymerization-IN-44 |
| Formula | C19H15Cl2N3O3S |
| Molar Mass | 436.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Na Li, et al.Discovery of 6-aryl-2-(3,4,5-trimethoxyphenyl)thiazole[3,2-b][1,2,4] |
Tubulin polymerization-IN-44
CAS: F: C19H15Cl2N3O3S W: 436.31
Tubulinpolymer-in-44 (compound 7w) is a strong and effective Tubulin inhibitor, with an IC50 value of 0.21 μM. Tubulinp
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