Tubulin polymerization-IN-13_product_DataBase

Bioactivity	Tubulin polymerization-IN-13 (Compound 4f) is a tubulin polymerization inhibitor (IC50=0.37 μM). Tubulin polymerization-IN-13 shows anti-proliferative activity against cancer cells, induces apoptosis and potential antivascular activity[1].
Invitro	Tubulin polymerization-IN-13 (0.005-2.8 nM) treatment inhibits tumor cell proliferation[1].Tubulin polymerization-IN-13 (8.7-10 μM) is non-toxic in non-tumor cells[1].Tubulin polymerization-IN-13 (1-50 nM; 24 h) treatment induces cell cycle arrest in G2/M[1].Tubulin polymerization-IN-13 (10 nM; 24 and 48 h) treatment induces cell apoptosis[1].Tubulin polymerization-IN-13 (10-100 nM; 24 h) treatment induces alteration of the microtubule network[1]. Cell Proliferation Assay[1] Cell Line:
Name	Tubulin polymerization-IN-13
CAS	2426665-56-5
Formula	C20H21NO6
Molar Mass	371.38
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

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