| Bioactivity | Tubulin inhibitor 14 is a potent NQO2 (quinone oxidoreductase 2) inhibitor with an IC50 of 1.0 μM. Tubulin inhibitor 14 also inhibits tubulin polymerization and the formation of endothelial cell capillary-like tubes. Tubulin inhibitor 14 is a microtubule-destabilizing agent with potential tumor-selectivity and antiangiogenic and vascular disrupting features[1]. |
| Invitro | Tubulin inhibitor 14 (compound 4) (0-20 μM, 96 h) inhibits cancer cells proliferation [1].Tubulin inhibitor 14 (1-5 μM, 24 or 48 h) causes G2/M cell cycle arrest[1].Tubulin inhibitor 14 (0.5-1 μM, 24 h) induces SNU423 cell apoptosis[1].Tubulin inhibitor 14 (0.5-1 μM, 24 h) disrupts the cytoskeleton network in endothelial cells[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | Tubulin inhibitor 14 |
| Formula | C15H9F2NO |
| Molar Mass | 257.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Tubulin inhibitor 14
CAS: F: C15H9F2NO W: 257.23
Tubulin inhibitor 14 is a potent NQO2 (quinone oxidoreductase 2) inhibitor with an IC50 of 1.0 μM. Tubulin inhibitor 14
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.