Bioactivity | Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM[1]. |
Target | EC50: 5 nM (Trypanosoma brucei) |
Invitro | Tuberculosis inhibitor 1 is selective over other parasites, such as Trypanosoma cruzi and Plasmodium falciparum (T. cruzi EC50 8120 nM, P. falciparum EC50 3624 nM)[1]. |
Name | Tuberculosis inhibitor 1 |
CAS | 2230810-28-1 |
Formula | C34H37N5O3 |
Molar Mass | 563.69 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ferrigno F, et al. Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitorsof Trypanosoma brucei growth in vitro. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3689-3692. |