| Bioactivity | Trypanothione synthetase-IN-5 (compound 9) is a trypanothione reductase (TR) inhibitor, with an IC50 of 20.5 μM for Leishmania infantum TR. Trypanothione synthetase-IN-5 also has inhibitory activity for human glutathione reductase (hGR), with an IC50 of 62.4 μM[1]. |
| Name | Trypanothione synthetase-IN-5 |
| Formula | C35H39F2IN4O3 |
| Molar Mass | 728.61 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Exertier C, et al. Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis. J Med Chem. 2024 Jan 11;67(1):402-419. |
Trypanothione synthetase-IN-5
CAS: F: C35H39F2IN4O3 W: 728.61
Trypanothione synthetase-IN-5 (compound 9) is a trypanothione reductase (TR) inhibitor, with an IC50 of 20.5 μM for Lei
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