| Bioactivity | TrxR1-IN-B19 (GO-Y015) (Compound B19) is a Curcumin (HY-N0005) derivative and colvalent TrxR1 inhibitor. TrxR1-IN-B19 inhibits TrxR1 enzyme activity to elevate oxidative stress, and then induce ROS-mediated ER Stress and mitochondrial dysfunction, subsequently resulting in cell cycle arrest and apoptosis[1]. |
| CAS | 170950-29-5 |
| Formula | C21H22O5 |
| Molar Mass | 354.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen W,et al. Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation. Oncotarget. 2016 Mar 29;7(13):16593-609. |
TrxR1-IN-B19
CAS: 170950-29-5 F: C21H22O5 W: 354.40
TrxR1-IN-B19 (GO-Y015) (Compound B19) is a Curcumin (HY-N0005) derivative and colvalent TrxR1 inhibitor. TrxR1-IN-B19 in
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.