Bioactivity | True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival[1][2]. |
In Vivo | True Blue can label dorsal root ganglion neurons (DRGNs) and motoneurons (MNs) by soaking the cut sciatic nerve of adult female rats, and does not affect neuronal survival whenever 4 days or 20 weeks after soak[2]. |
Name | True Blue |
CAS | 71431-30-6 |
Formula | C20H18Cl2N4O2 |
Molar Mass | 417.29 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. M Bentivoglio, et al. Fuorescent retrograde neuronal labeling in rat by means of substances binding specifically to adenine-thymine rich DNA. Neurosci Lett. 1979 May;12(2-3):235-40. [2]. W T Garrett, et al. Fluoro-Gold's toxicity makes it inferior to True Blue for long-term studies of dorsal root ganglion neurons and motoneurons. Neurosci Lett. 1991 Jul 8;128(1):137-9. |