| Bioactivity | Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors[1][2]. |
| Target | mAChRs |
| Name | Trospium chloride |
| CAS | 10405-02-4 |
| Formula | C25H30ClNO3 |
| Molar Mass | 427.96 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. David RP Guay. Trospium chloride: an update on a quaternary anticholinergic for treatment of urge urinary incontinence. Ther Clin Risk Manag. 2005 Jun; 1(2): 157–167. [2]. Eric S Rovner, et al. Trospium chloride in the management of overactive bladder. Drugs. 2004;64(21):2433-46. |
Trospium chloride
CAS: 10405-02-4 F: C25H30ClNO3 W: 427.96
Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs),
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