| Bioactivity | TrkA-IN-8 (Compound 2) is a TrkA inhibitor with a Kd value of 3.3 µM. RTKs-IN-1 exhibits concentration-dependent inhibition of cell proliferation in lung cancer cell lines. RTKs-IN-1 holds potential for research in non-small cell lung cancer [1]. |
| CAS | 128889-33-8 |
| Formula | C20H16N4 |
| Molar Mass | 312.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kim J Y, et al. Effects of Tropomyosin-related kinase a inhibitors on the proliferation of human lung cancer cells[J]. Bulletin of the Korean Chemical Society, 2013, 34(4): 1293-1295. |