| Bioactivity | TrkA-IN-1 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 of 99 nM in a cell-based assay. TrkA-IN-1 has analgesic activity[1]. | ||||||||||||
| Name | TrkA-IN-1 | ||||||||||||
| CAS | 1680179-43-4 | ||||||||||||
| Formula | C25H20N4O | ||||||||||||
| Molar Mass | 392.45 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Su HP , et al. Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E297-E306. |