| Bioactivity | Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA, compound 3) is an accelerating ligand in the copper-catalyzed azide-alkyne cycloaddition reaction (CuAAC). Tris(3-hydroxypropyltriazolylmethyl)amine protects the histidine moiety of biomolecules in a manner proportional to ligand concentration[1]. | ||||||||||||
| Name | Tris(3-hydroxypropyltriazolylmethyl)amine | ||||||||||||
| CAS | 760952-88-3 | ||||||||||||
| Formula | C18H30N10O3 | ||||||||||||
| Molar Mass | 434.50 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Hong V, et al. Analysis and optimization of copper-catalyzed azide-alkyne cycloaddition for bioconjugation. Angew Chem Int Ed Engl. 2009;48(52):9879-83. |