| Bioactivity | Tripolin A ((E)-Tripolin A) is a specific non-ATP competitive Aurora A kinase inhibitor, with IC50 values of 1.5 μM and 7 μM for Aurora A and Aurora B, respectively[1]. |
| Target | IC50: 1.5 μM (Aurora A), 7 μM (Aurora A). |
| Invitro | Tripolin A induces mitotic spindle defects and spindle pole abnormalities[1]. |
| Name | Tripolin A |
| CAS | 1148118-92-6 |
| Formula | C15H11NO3 |
| Molar Mass | 253.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Iliana A Kesisova, et al. Tripolin A, a Novel Small-Molecule Inhibitor of Aurora A Kinase, Reveals New Regulation of HURP's Distribution on Microtubules. PLoS One. 2013;8(3):e58485. |
Tripolin A
CAS: 1148118-92-6 F: C15H11NO3 W: 253.25
Tripolin A ((E)-Tripolin A) is a specific non-ATP competitive Aurora A kinase inhibitor, with IC50 values of 1.5 μM and
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