| Bioactivity | Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. |
| Target | D2 receptor |
| Invitro | Trimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center[1]. |
| In Vivo | The oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration[1]. |
| Name | Trimethobenzamide hydrochloride |
| CAS | 554-92-7 |
| Formula | C21H29ClN2O5 |
| Molar Mass | 424.92 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Smith HS, et al. Dopamine receptor antagonists. Ann Palliat Med. 2012 Jul;1(2):137-42. |
Trimethobenzamide hydrochloride
CAS: 554-92-7 F: C21H29ClN2O5 W: 424.92
Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent naus
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.