| Bioactivity | Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity[1][2]. |
| Invitro | Triiodothyronine (T3, 100 nM) stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[2]. Liothyronine binds to human β1 thyroid hormone receptor (hTRβ1), and change its conformation. Triiodothyronine promotes growth, induces differentiation and regualtes metabolic effects[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Triiodothyronine sulfate 相关抗体: |
| CAS | 31135-55-4 |
| Formula | C15H12I3NO7S |
| Molar Mass | 731.04 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. J S LoPresti, et al. 3,5,3'-Triiodothyronine (T3) sulfate: a major metabolite in T3 metabolism in man. J Clin Endocrinol Metab. 1994 Mar;78(3):688-92. [2]. Lin KH, et al. Stimulation of proliferation by 3,3',5-triiodo-L-thyronine in poorly differentiated human hepatocarcinoma cells overexpressing beta 1 thyroid hormone receptor. Cancer Lett. 1994 Oct 14;85(2):189-94. [3]. Bhat MK, et al. Conformational changes of human beta 1 thyroid hormone receptor induced by binding of 3,3',5-triiodo-L-thyronine. Biochem Biophys Res Commun. 1993 Aug 31;195(1):385-92. |
Triiodothyronine sulfate
CAS: 31135-55-4 F: C15H12I3NO7S W: 731.04
Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active
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