| Bioactivity | Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis[1]. |
| Name | Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH |
| Formula | C84H134N10O39 |
| Molar Mass | 1908.01 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Neal MD, et al. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013;8(6):e65779. Published 2013 Jun 12. |
Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH
CAS: F: C84H134N10O39 W: 1908.01
Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-
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