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Topoisomerase inhibitor 4

CAS: 3021532-95-3 F: C30H28F3IN4O3 W: 676.47

Topoisomerase inhibitor 4 (compound 45) is a potent Topoisomerase1/2 inhibitor. Topoisomerase inhibitor 4 causes cell cy
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Bioactivity Topoisomerase inhibitor 4 (compound 45) is a potent Topoisomerase1/2 inhibitor. Topoisomerase inhibitor 4 causes cell cycle arrest in the G2/M phase by inducing Apoptosis. Topoisomerase inhibitor 4 has antitumor activity[1].
CAS 3021532-95-3
Formula C30H28F3IN4O3
Molar Mass 676.47
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Wei X, et al. Identification of a novel 10-hydroxyevodiamine prodrug as a potent topoisomerase inhibitor with improved aqueous solubility for treatment of hepatocellular carcinoma. Eur J Med Chem. 2024 Sep 1;279:116807.