| Bioactivity | Topoisomerase IV inhibitor 2 (compound 5d) is a potent DNA topoisomerase IV (TOPO IV) inhibitor with IC50s of 0.35 μM and 0.55 μM for TOPO IV and DNA gyrase, respectively. Topoisomerase IV inhibitor 2 has anti-bacterial activity, with MICs of 1.985 μM and 0.744 μM in Staphylococcus aureus Newman and Escherichia coli ATCC8739, respectively[1]. |
| Name | Topoisomerase IV inhibitor 2 |
| CAS | 2883403-36-7 |
| Formula | C33H30FN7O6S |
| Molar Mass | 671.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ibrahim NM, et al. Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects. Eur J Med Chem. 2022;228:114021. |
Topoisomerase IV inhibitor 2
CAS: 2883403-36-7 F: C33H30FN7O6S W: 671.70
Topoisomerase IV inhibitor 2 (compound 5d) is a potent DNA topoisomerase IV (TOPO IV) inhibitor with IC50s of 0.35 μM a
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.