| Bioactivity | Topoisomerase IIα-IN-8 (compound 15) is a weak human DNA topoisomerase IIa (htIIa) inhibitor, with an IC50 of 462 ± 38.0 μM[1]. | ||||||||||||
| Name | Topoisomerase IIα-IN-8 | ||||||||||||
| CAS | 1251578-67-2 | ||||||||||||
| Formula | C15H15FN6O | ||||||||||||
| Molar Mass | 314.32 | ||||||||||||
| Appearance | 粉末 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Barbara Pogorelčnik, et al. Discovery of Mono- and Disubstituted 1H-Pyrazolo[3,4]pyrimidines and 9H-Purines as Catalytic Inhibitors of Human DNA Topoisomerase II. ChemMedChem, 2015. |
Topoisomerase IIα-IN-8
CAS: 1251578-67-2 F: C15H15FN6O W: 314.32
Topoisomerase IIα-IN-8 (compound 15) is a weak human DNA topoisomerase IIa (htIIa) inhibitor, with an IC50 of 462 ± 38
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