Bioactivity | Topoisomerase II/EGFR-IN-1 is topoisomerase II/EGFR dual inhibitor. Topoisomerase II/EGFR-IN-1 has superior cytotoxic activity to MCF-7, A549 and HCT-116 cell lines, displays strong apoptotic activity and can be used for the research of cancer[1]. |
Name | Topoisomerase II/EGFR-IN-1 |
Formula | C21H8N4O5S |
Molar Mass | 428.38 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mourad M A E, et al. Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho [2′, 3′: 4, 5] thiazolo [3, 2-a] pyrimidine hybrids as potential anticancer agents with apoptosis inducing activity [J]. Journal of Enzyme Inhibition and Medicinal Chemistry, 2023, 38(1): 2205043. |