| Bioactivity | Topoisomerase II inhibitor 19 (compound 5h) is a DNA intercalator and topoisomerase II inhibitor (IC50 value of 0.34 μM). Topoisomerase II inhibitor 19 would induce detectable potent damage in ctDNA[1]. |
| Invitro | Topoisomerase II inhibitor 19 (compound 5h; 24h) 通过将细胞周期阻滞在 S 期来抑制 MCF-7 细胞的细胞增殖[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Topoisomerase II inhibitor 19 相关抗体: |
| Formula | C27H16ClN3OS |
| Molar Mass | 465.95 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Asmaa H Mohamed, et al. New imidazole-2-thiones linked to acenaphythylenone as dual DNA intercalators and topoisomerase II inhibitors: structural optimization, docking, and apoptosis studies. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2311818. |
Topoisomerase II inhibitor 19
CAS: F: C27H16ClN3OS W: 465.95
Topoisomerase II inhibitor 19 (compound 5h) is a DNA intercalator and topoisomerase II inhibitor (IC50 value of 0.34 μ
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.