| Bioactivity | Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM[1]. |
| Target | 34.81 μM |
| Name | Topoisomerase I inhibitor 9 |
| CAS | 1228150-86-4 |
| Formula | C23H15Br2FN2 |
| Molar Mass | 498.19 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kour P, et al. Design, synthesis, and biological evaluation of 3,3'-diindolylmethane N-linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity. RSC Med Chem. 2023;14(10):2100-2114. Published 2023 Aug 30. |