| Bioactivity | TopBP1-IN-1 is a TopBP1 inhibitor. TopBP1-IN-1 has a synergistic effect with PARP inhibitors. TopBP1-IN-1 has antitumor activity [1]. |
| Target | Topoisomerase IIβ-binding Protein 1 (TopBP1) |
| Name | TopBP1-IN-1 |
| CAS | 1212595-23-7 |
| Formula | C30H34N4O |
| Molar Mass | 466.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lin FT, et al. A small-molecule inhibitor of TopBP1 exerts anti-MYC activity and synergy with PARP inhibitors. Proc Natl Acad Sci U S A. 2023 Oct 31;120(44):e2307793120. |
TopBP1-IN-1
CAS: 1212595-23-7 F: C30H34N4O W: 466.62
TopBP1-IN-1 is a TopBP1 inhibitor. TopBP1-IN-1 has a synergistic effect with PARP inhibitors. TopBP1-IN-1 has antitumor
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