| Bioactivity | Toddalolactone, a main component of Toddalia asiatica, inhibits the activity of recombinant human plasminogen activator inhibitor-1 (PAI-1), with an IC50 value of 37.31 μM[1]. | ||||||||||||
| Invitro | Toddalolactone, a natural coumarin, inhibits PAI-1 activity by preventing the formation of a stable PAI-1/uPA covalent complex, suggesting that the inhibitory effect of Toddalolactone may be due to the interference of close contact between plasminogen activator and the active center of PAI-1[1]. | ||||||||||||
| Name | Toddalolactone | ||||||||||||
| CAS | 483-90-9 | ||||||||||||
| Formula | C16H20O6 | ||||||||||||
| Molar Mass | 308.33 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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