| Bioactivity | Toddaculin is a natural coumarin that can induce differentiation and apoptosis in leukemic cells. Toddaculin suppresses excess osteoclast activity and enhances osteoblast differentiation and mineralization. Toddaculin also exhibits anti-inflammatory activity[1][2][3]. |
| Invitro | Toddaculin (5-250 μM; 24-72 h) shows anti-proliferative activity in U-937 cells, with an IC50 of 51.38 μM[1].Toddaculin (25-250 μM; 24-48 h) induces partial differentiation in U-937 leukemic cells[1]. |
| Name | Toddaculin |
| CAS | 4335-12-0 |
| Formula | C16H18O4 |
| Molar Mass | 274.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Toddaculin
CAS: 4335-12-0 F: C16H18O4 W: 274.31
Toddaculin is a natural coumarin that can induce differentiation and apoptosis in leukemic cells. Toddaculin suppresses
Data collection：peptidedb@qq.com
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