| Bioactivity | Tiprelestat is a potent human neutrophil elastase inhibitor. Tiprelestat has antimicrobial and anti-inflammatory activities. Tiprelestat can be used in the research of inflammation/immune disease[1]. |
| Invitro | Tiprelestat (4 and 8 μM) inhibits P. aeruginosa-secreted peptidase[3].Tiprelestat (10 μg/mL, 1 h) inhibits LPS-induced MCP-1 production in U937 cells[4].Tiprelestat (10 μg/mL, 1 h) down-regulates LPS-induced AP-1 and NF-κB activation in U937 cells[4]. Western Blot Analysis[4] Cell Line: |
| Name | Tiprelestat |
| CAS | 820211-82-3 |
| Formula | C254H416N72O75S10 |
| Molar Mass | 5999.09 |
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| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Tiprelestat
CAS: 820211-82-3 F: C254H416N72O75S10 W: 5999.09
Tiprelestat (Elafin) is a potent Human neutrophil elastase inhibitor.Elafin is identical to the human protein elafin wit
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This product is for research use only, not for human use. We do not sell to patients.