| Bioactivity | Timcodar is a macrolide agent, and studies have shown that during adipogenesis, timcodar can significantly inhibit fat accumulation, with an effect similar to that of rapamycin. However, unlike rapamycin, timcodar does not cause immunosuppression and glucose resistance. In addition, timcodar can effectively inhibit the adipogenic transcriptional regulators PPAR?? and C/EBP??, thereby inhibiting genes involved in fat accumulation. These studies lay the foundation for timcodar as a potential anti-obesity therapy, as obesity is becoming a global epidemic. |
| CAS | 179033-51-3 |
| Formula | C43H45ClN4O6 |
| Molar Mass | 749.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Timcodar (VX‐853) Is a Non‐FKBP12 Binding Macrolide Derivative That Inhibits PPARγ and Suppresses Adipogenesis |
Timcodar
CAS: 179033-51-3 F: C43H45ClN4O6 W: 749.29
Timcodar is a macrolide agent, and studies have shown that during adipogenesis, timcodar can significantly inhibit fat a
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