| Bioactivity | Tilivalline is an enterotoxin that can be produced by Klebsiella oxytoca. Tilivalline shows cytotoxicity against carcinoma cells. Tilivalline induces epithelial apoptosis. Tilivalline causes antibiotic-associated hemorrhagic colitis (AAHC)[1][2]. |
| CAS | 80279-24-9 |
| Formula | C20H19N3O2 |
| Molar Mass | 333.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hering NA, et al. Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment. Int J Mol Sci. 2019 Nov 8;20(22):5595. [2]. von Tesmar A, et al. Biosynthesis of the Klebsiella oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development. ACS Chem Biol. 2018 Mar 16;13(3):812-819. |
Tilivalline
CAS: 80279-24-9 F: C20H19N3O2 W: 333.38
Tilivalline is an enterotoxin that can be produced by Klebsiella oxytoca. Tilivalline shows cytotoxicity against carcino
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