Bioactivity | Tiger17 is an effective wound healing agent. Tiger17 is able to induce the secretion of TGF-β1 and acts through the Smad signaling pathway, specifically promoting wound healing by increasing the phosphorylation of Smad2 and Smad3. Tiger17, as a polypeptide that promotes endogenous wound healing agents, can be used to study wound healing[1]. |
CAS | 1647121-94-5 |
Sequence | Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2 (Disulfidebridge:Cys2-Cys10) |
Shortening | WCKPKPKPRCH-NH2 (Disulfidebridge:Cys2-Cys10) |
Formula | C62H99N21O11S2 |
Molar Mass | 1378.71 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tang J, et al. A small peptide with potential ability to promote wound healing[J]. PloS one, 2014, 9(3): e92082. |