Bioactivity | Tiamenidine hydrochloride (HOE 440 hydrochloride) is a centrally acting α1-adrenergic receptor antagonist with hypotensive activity. Tiamenidine hydrochloride regulates blood pressure levels by binding to α1 receptors. Tiamenidine hydrochloride can be used in the study of hypertension[1]. |
CAS | 51274-83-0 |
Formula | C8H11Cl2N3S |
Molar Mass | 252.16 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. D M Roden, et al. Electrophysiologic and hemodynamic effects of chronic oral therapy with the alpha 2-agonists clonidine and tiamenidine in hypertensive volunteers. Clin Pharmacol Ther. 1988 Jun;43(6):648-54. [2]. Quantitative determination of tiamenidine hydrochloride in human serum using gas chromatography mass spectrometry |