| Bioactivity | Thymine-13C5,15N2 (5-Methyluacil-13C5,15N2) is 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[1]. |
| CAS | 2483830-13-1 |
| Formula | 13C5H615N2O2 |
| Molar Mass | 133.06 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45(11 Pt 1):5553-6. |
Thymine-13C5,15N,15N2
CAS: 2483830-13-1 F: 13C5H615N2O2 W: 133.06
Thymine-13C5,15N2 (5-Methyluacil-13C5,15N2) is 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in th
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