| Bioactivity | Thymidine 3',5'-disphosphate (Deoxythymidine 3′,5′-diphosphate; pdTp) is a selective small molecule inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the miRNA regulatory complex RISC subunit) and inhibits SND1 activity. Thymidine 3',5'-disphosphate exhibits anti-tumor efficacy in vivo[1]. |
| Invitro | Thymidine 3',5'-disphosphate (200 µM；18 h) 通过抑制葡萄球菌核酸酶和含有 1 的都铎结构域 (SND1) 酶活性显著降低 WT 和 Alb/SND1 (特异性过表达 SND1 转基因小鼠) 肝细胞中 p65 表达水平和 p65 核易位。Thymidine 3',5'-disphosphate 抑制了 WT 和 Alb/SND1 肝细胞的球形形成[1]。 |
| Name | Thymidine 3',5'-disphosphate |
| CAS | 2863-04-9 |
| Formula | C10H16N2O11P2 |
| Molar Mass | 402.19 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Thymidine 3',5'-disphosphate
CAS: 2863-04-9 F: C10H16N2O11P2 W: 402.19
Thymidine 3',5'-disphosphate (Deoxythymidine 3′,5′-diphosphate; pdTp) is a selective small molecule inhibitor of staph
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.