| Bioactivity | Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium is a selective inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the MicroRNA regulatory complex RISC subunit) and [3,5-2H2] tyrosyl nuclease. Thymidine 3',5'-diphosphate tetrasodium has anti-tumor activity and can also be used as a catalyst in biochemical reactions[1][2]. |
| Invitro | Thymidine 3',5'-diphosphate tetrasodium (200 µM；18 h) 通过抑制葡萄球菌核酸酶和含有 1 的都铎结构域 (SND1) 酶活性显著降低 WT 和 Alb/SND1 (特异性过表达 SND1 转基因小鼠) 肝细胞中 p65 表达水平和 p65 核易位。Thymidine 3',5'-diphosphate tetrasodium 抑制了 WT 和 Alb/SND1 肝细胞的球形形成[1]。 |
| Name | Thymidine 3',5'-diphosphate tetrasodium |
| CAS | 118675-87-9 |
| Formula | C10H12N2Na4O11P2 |
| Molar Mass | 490.12 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Thymidine 3',5'-diphosphate tetrasodium
CAS: 118675-87-9 F: C10H12N2Na4O11P2 W: 490.12
Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium is a selective inhibitor of staphylococcal
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