| Bioactivity | Thioproperazine (RP 7843) is an orally active antipsychotic agent with calming, antiemetic activity. Thioproperazine is effective in promoting the release of dopamine in rat striatum. Thioproperazine can be used in studies of schizophrenia and bipolar disorder[1]. |
| In Vivo | Thioproperazine (5 mg/kg; i.p.; single) increases accumulation of dopamine in rat striatum[1]. Animal Model: |
| Name | Thioproperazine |
| CAS | 316-81-4 |
| Formula | C22H30N4O2S2 |
| Molar Mass | 446.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cheramy A, et al. Increased release of dopane from striatal dopaminergic terminals in the rat after treatment with a neuroleptic: thioproperazine. Eur J Pharmacol. 1970 May;10(2):206-14. |
Thioproperazine
CAS: 316-81-4 F: C22H30N4O2S2 W: 446.63
Thioproperazine (RP 7843) is an orally active antipsychotic agent with calming, antiemetic activity. Thioproperazine is
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