| Bioactivity | Thioether-cyclized helix B peptide, CHBP can improve metabolic stability and renoprotective effect through inducing autophagy via inhibition of mTORC1 and activation of mTORC2[1]. |
| Name | Thioether-cyclized helix B peptide, CHBP |
| CAS | 1453840-35-1 |
| Sequence | Ac-GIn-Glu-GIn-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-Cys-NH2 (Cyclization via thioether-bond through N-terminal Me and -SH of Cys) |
| Shortening | Ac-QEQLERALNSSC-NH2 (Cyclization via thioether-bond through N-terminal Me and -SH of Cys) |
| Formula | C56H93N19O22S |
| Molar Mass | 1416.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cheng Yang, et al. A novel proteolysis-resistant cyclic helix B peptide ameliorates kidney ischemia reperfusion injury. Biochim Biophys Acta. 2014 Nov;1842(11):2306-17. |
Thioether-cyclized helix B peptide, CHBP
CAS: 1453840-35-1 F: C56H93N19O22S W: 1416.52
Thioether-cyclized helix B peptide, CHBP can improve metabolic stability and renoprotective effect through inducing auto
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