| Bioactivity | Thioether-cyclized helix B peptide, CHBP (TFA) is the TFA form of Thioether-cyclized helix B peptide, CHBP (HY-P5984). Thioether-cyclized helix B peptide, CHBP (TFA) can improve metabolic stability and renoprotective effect through inducing autophagy via inhibition of mTORC1 and activation of mTORC2[1]. |
| Name | Thioether-cyclized helix B peptide, CHBP TFA |
| Sequence | Ac-GIn-Glu-GIn-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-Cys-NH2 (TFA salt) (Cyclization via thioether-bond through N-terminal Me and -SH of Cys) |
| Shortening | Ac-QEQLERALNSSC-NH2 (TFA salt) (Cyclization via thioether-bond through N-terminal Me and -SH of Cys) |
| Formula | C56H93N19O22S.xC2HF3O2 |
| Molar Mass | 1416.52 (free base) |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cheng Yang, et al. A novel proteolysis-resistant cyclic helix B peptide ameliorates kidney ischemia reperfusion injury. Biochim Biophys Acta. 2014 Nov;1842(11):2306-17. |
Thioether-cyclized helix B peptide, CHBP TFA
CAS: F: C56H93N19O22S.xC2HF3O2 W: 1416.52 (free base)
Thioether-cyclized helix B peptide, CHBP (TFA) is the TFA form of Thioether-cyclized helix B peptide, CHBP (HY-P5984). T
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This product is for research use only, not for human use. We do not sell to patients.