Bioactivity | Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 is the E3 ubiquitin ligase ligand and linker of PROTAC (R)-NX-2127 (HY-153220A), which can be used in cancer research[1]. |
Formula | C29H33N5O4 |
Molar Mass | 515.60 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Daniel W Robbins, et al. Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies. J Med Chem. 2024 Feb 22;67(4):2321-2336. |