| Bioactivity | Thalidomide-piperidine-C2-piperazine-Boc is an E3 ligase ligand-linker conjugate that incorporates the Thalidomide (HY-130639) based cereblon ligand and a linker used in PROTAC technology. Thalidomide-piperidine-C2-piperazine-Boc can be used for synthesis of PROTACs[1]. |
| Formula | C29H39N5O6 |
| Molar Mass | 553.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Danli Zhou, et al. Discovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity. J Med Chem. 2023 Apr 13;66(7):4979-4998. |
Thalidomide-piperidine-C2-piperazine-Boc
CAS: F: C29H39N5O6 W: 553.65
Thalidomide-piperidine-C2-piperazine-Boc is an E3 ligase ligand-linker conjugate that incorporates the Thalidomide (HY-1
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