| Bioactivity | Thalidomide-d4 is a deuterium labeled Thalidomide. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ~250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties[1][2]. | ||||||||||||
| Name | Thalidomide-d4 | ||||||||||||
| CAS | 1219177-18-0 | ||||||||||||
| Formula | C13H6D4N2O4 | ||||||||||||
| Molar Mass | 262.25 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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